
Antique Microscope |

Patent - Nissenbaum
Diagnostotube |

Article - Nissenbaum
Diagnostotube |
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Diagram of the Nissenbaum
Diagnostotube |

Surgical World Article
about the Nissenbaum Diagnostotube |

The Nissenbaum
Diagnostotube |
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The Story Behind the
Discovery of Nissenbaum's Fixative |
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Even in his early youth and adolescence, Dr. Nissenbaum
had a profound love of science. He was a deeply curious young man with a keen intelligence
and amazing manual dexterity and precision. He had a lifelong passion to understand how
things worked. One of his fondest childhood memories was purchasing a used, half-broken
antique microscope which he used to explore the startling world of the protozoa. In high
school, he was given special permission to utilize the facilities at the Biology
laboratory of Yeshiva University. While there, he made the extraordinary discovery of
Nissenbaums Fixative, the first-ever method of rapidly fixing ciliated protozoa to
slides. This was nothing less than a revolution in the field of Microbiology and is
now seen as one of the great advances of the twentieth century in this field (See article
above).
As a young physician, he also invented
the Nissenbaum Diagnostotube, which was used to localize the site of internal upper
gastrointestinal bleeding. It is acknowledged as one of the major advances in Endoscopy of
the early 1960s. Finally, he developed a rotating bracket and accessories that were
one of the first to allow physicians to generate color photographs of the digestive
system. |